CHRONO-LOG® Platelet Function Reagents

CHRONO-LOG PLatelet Function Reagents Provide High Accuracy and Low Costs Per Test

Chrono-log offers a complete line of highly concentrated platelet aggregation reagents, requiring only micro-portions per test. The standard aggregation reagents: Thrombin, ADP, Collagen, Ristocetin, Epinephrine and Arachidonic Acid are available, as well as CHRONO-LUME^® and ATP Standard reagents for determination of dense granule release when performing Lumi Aggregation.

Please review this year-long study which confirmed the exceptional stability of Chrono-log aggregation reagents.

CHRONO-LOG^® CHRONO-PAR^® Reagents are validated for use in both Whole Blood and PRP samples.

ADP

Each vial contains 2.5mg of lyophilized adenosine diphosphate. Performs 500 to 1000 tests in PRP or Whole Blood samples.

Collagen

Each vial contains 1mg of native Collagen fibrils (type I) from equine tendons suspended in isotonic glucose solution of pH 2.7. Performs 500 to 1000 tests in PRP or Whole Blood samples.

Ristocetin

Each vial contains 62.5mg of stabilized freeze dried Ristocetin. Performs 62 to 125 tests in PRP or Whole Blood samples.

Arachidonic Acid

Each vial contains a minimum of 10mg of Arachidonic Acid, purity better than 99%. Included is a vial containing 100mg bovine albumin, fraction V powder, 96% to 99% purity. Performs 70 to 140 tests in PRP or Whole Blood samples.

Epinephrine

Lyophilized preparation of 1-Epinephrine bitartarate with stabilizers. Performs 1000 or more tests in PRP samples.

Thrombin

Each vial contains a minimum of 10 units of lyophilized Thrombin from human plasma. Performs 10 to 20 tests in PRP or Whole Blood samples.

CHRONO-LUME^® Reagents

For Performing Secretion Study Simultaneously with Aggregation

For the quantitation of ATP Release. Supplied as 2 μmole of lyophilized adenosine 5′ triphosphate. 5 μL added to any size test sample provides a 2 nmole standard.

Reagent for measurement of ATP release. Each vial contains 0.2 mg luciferin, 22,000 units d-luciferase plus magnesium sulfate, human serum albumin, stabilizers and buffer. Kit includes 4 vials of CHRONO- LUME plus a vial of lyophilized adenosine 5′ triphosphate for use as an ATP Standard. Performs 50 to 100 tests in PRP or Whole Blood samples.

Ristocetin CoFactor Assay

For the Quantitation of Ristocetin CoFactor Activity

Ristocetin CoFactor Assay Kit
(von Willebrand Factor Assay)

CHRONO-LOG Ristocetin CoFactor Assay Kit

For use in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma. The following Materials included provide volumes sufficient to run 15 determinations: Ristocetin, 7.5 mg/vial; Lyophilized Human Platelets, 6 mL; von Willebrand Reference Plasma, Normal, 1.0 mL; von Willebrand Reference Plasma, Deficient, 0.5 mL; Tris Buffered Saline (TBA) 12 mL.

Lyophilized Human
Platelets

For use in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma. Each vial provides 6 mL of Platelets following reconstitution with Tris Buffered Saline (TBS) for performing up to 15 determinations.

Ristocetin

For use in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma. Each vial contains 7.5 mg of freeze dried Ristocetin for performing up to 15 determinations @ 1.0 mg/mL.

vW Reference Plasma
Normal

For use in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma. Each vial contains dried human plasma standardized for Ristocetin Cofactor Activity, 1.0 mL.

vW Reference Plasma
Deficient

For use in the quantitative determination of Factor VIII Ristocetin Cofactor Activity in citrated plasma. Each vial contains dried human plasma derived from human congenital von Willebrand patients, 0.5 mL.

All CHRONO-LOG^® Platelet Function Reagents are FDA approved and CE marked and can be used for clinical and pharmaceutical studies.

CHRONO-LOG Platelet Function Reagents

CHRONO-LOG® Platelet Function Reagents